Donald Ye, MD

Dr. Donald Ye has studied the inner workings of the brain and the nervous system his entire career, seeking better ways to fix problems that afflict the brain and spine. As a student, researcher, and clinician, he has had challenged himself to better understand complex neurological pathways and to provide the best solutions for patients and their families with thoughtful clinical judgment and realistic expectations.

Dr. Ye graduated from the University of California, Berkeley as a double major with Highest Honors in Psychology and High Distinction in Molecular and Cell Biology focusing his research on functional imaging of cognitive pathways. He continued his medical education at the Cleveland Clinic Lerner College of Medicine at Case Western Reserve University where he fostered his interest in neurosurgery and neurosurgical oncology. During this time, as a Howard Hughes Medical Institute Medical Research Scholars Program, he spent time studying rare tumor syndromes and molecular pathways involved in glioblastoma in the Surgical Neurology Branch at the National Institutes of Health in Bethesda, MD.

He completed his neurosurgical residency training at Thomas Jefferson University Hospital in Philadelphia, PA. Under the leadership of neurosurgical pioneer – Dr. Robert Rosenwasser – he learned the importance of being a well-rounded surgeon capable of treating diseases with all of the tools and techniques available and tailoring them to best suit each individual patient. Trained in the breadth of traditional and minimally invasive approaches to the brain and spine, Dr. Ye understands the value of minimizing risk and maximizing recovery to provide the best overall outcome for his patients. 

Dr. Ye joins Inland Neurosurgery Institute to provide the same high-quality, patient-centric neurosurgical care that his colleagues have provided to the community for decades.

In his free time, Dr. Ye enjoys spending time with his wife and daughter, reading, cooking, and traveling.

EDUCATION

• 2009: Bachelor of Arts in Molecular and Cell Biology and Psychology (High Distinction in General Scholarship)
• 2014: Medical Doctorate (MD) from Cleveland Clinic Lerner College of Medicine at Case Western Reserve
  University,
• 2014-2021: Neurosurgery Residency at Thomas Jefferson University Hospital
  
  

ASSOCIATIONS & MEMBERSHIPS

• Resident Member, American Association of Neurological Surgeons
• Resident Member, Congress of Neurological Surgeons
• Member, Pennsylvania Medical Society

ARTICLES & JOURNALS

• Ye, Donald Y., Kamran D. Bakhtian, Ashok R. Asthagiri, and Russell R. Lonser. 2012. “Effect of Pregnancy on Hemangioblastoma Development and Progression in von Hippel-Lindau Disease.” Journal of Neurosurgery 117 (5): 818–24. doi:10.3171/2012.7.JNS12367.
• Hafazalla, Karim, Donald Y. Ye, Timothy Chao, Mark Curtis, Christopher J. Farrell. 2020. “SEGA without clinical or genetically identifiable TSC: A case report.” Case Reports and Series in Surgery (in press)
• Al Saiegh, Fadi, Jacob Mazza, Karim Hafazalla, Thana Theofanis, Donald Y. Ye, Christian Hoelscher, James Harrop, James J. Evans, Pascal Jabbour, Robert H. Rosenwasser, Ashwini D. Sharan. 2020. “Developing standardized titles to classify the adverse events in 7,418 cranial and spinal neurosurgical procedures.” Clinical Neurology and Neurosurgery (in press).
• Sabourin, Victor, Jacob Mazza, Tomas Garzon, Jeffrey Head, Donald Y. Ye, Anthony Stefanelli, Fadi Al-Saiegh, Pascal Lavergne, and James Evans. 2020. “Internal Neurolysis with and without Microvascular Decompression for Trigeminal Neuralgia: Case Series.” World Neurosurgery, July. https://doi.org/10.1016/j.wneu.2020.06.206.
• Sabourin, Victor, Jacob Mazza, Tomas Garzon-Muvdi, Donald Y. Ye, Anthony Stefanelli, Fadi Al Saiegh, Daniel Tzou, and James J. Evans. 2019. “Internal Neurolysis With and Without Microvascular Decompression for Trigeminal Neuralgia.” Neurosurgery 66 (Supplement_1). https://doi.org/10.1093/neuros/nyz310_191.
• Gordon, Ira K., Jie Lu, Christian A. Graves, Kristin Huntoon, Jason M. Frerich, Ryan H. Hanson, Xiaoping Wang, Christopher Hong, Winson Ho, Michael J. Feldman, Barbara Ikejiri, Kheem Bisht, Xiaoyuan S. Chen, Anita Tandle, Chunzhang Yang, Tristram W. Arscott, Donald Ye, John D. Heiss, Russell R. Lonser, Kevin Camphausen, Zhengping Zhuang. 2015. “Protein Phosphatase 2A Inhibition with LB100 Enhances Radiation Induced Mitotic Catastrophe and Tumor Growth Delay in Glioblastoma.” Molecular Cancer Therapeutics 14 (7): 1540–47. doi:10.1158/1535-7163.MCT-14-0614.
• Yang, Chunzhang, Joey C. Matro, Kristin M. Huntoon, Donald Y. Ye, Thanh T. Huynh, Stephanie M. J. Fliedner, Jan Breza, Zhengping Zhuang, and Karel Pacak. 2012. “Missense Mutations in the Human SDHB Gene Increase Protein Degradation without Altering Intrinsic Enzymatic Function.” FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology 26 (11): 4506–16. doi:10.1096/fj.12-210146.
• Lu, Jie, Chunzhang Yang, Masako Chen, Donald Y. Ye, Russell R. Lonser, Roscoe O. Brady, and Zhengping Zhuang. 2011. “Histone Deacetylase Inhibitors Prevent the Degradation and Restore the Activity of Glucocerebrosidase in Gaucher Disease.” Proceedings of the National Academy of Sciences of the United States of America 108 (52): 21200–205. doi:10.1073/pnas.1119181109.
• Buchsbaum, Bradley R., Donald Ye, and Mark D’Esposito. 2011. “Recency Effects in the Inferior Parietal Lobe during Verbal Recognition Memory.” Frontiers in Human Neuroscience 5: 59. doi:10.3389/fnhum.2011.00059.
• Andrews, David W., Kevin D. Judy, Charles B. Scott, Samantha Garcia, Larry A. Harshyne, Lawrence Kenyon, Kiran Talekar, Adam Flanders, Kofi Buaku- Atsina, Lyndon Kim, Nina Martinez, Wenyin Shi, Maria Werner-Wasik, Haisong Liu, Mikhail Prosniak, Mark Curtis, Rhonda Kean, Donald Y. Ye, Emily Bongiorno, Aurore LeBrun, Sami Sauma, Kara Pigott, D. Craig Hooper. 2020. “IGV-001 in Newly Diagnosed Glioblastoma”. Journal of Clinical Oncology. Manuscript in submission.
• Ye, Donald Y., Thana Theofanis, Tomas Garzon-Muvdi, James J Evans. (in press). “Role of Hospital Medicine in the Management of Intracranial Brain Tumors” In R. Daniel and C. Harrop (Eds.), The Neurosurgery Hospitalist Manual. New York: Oxford University Press.
• Ye, Donald Y., Jonathan Riley, Ravichandra Madineni, Shannon Clark, Chengyuan Wu, Steven Falowski, Ashwini D. Sharan. (2018). “Spinal Cord Stimulation: Placement of Surgical Leads via Laminotomy: Techniques and Benefits.” In E. S. Krames, P. H. Peckham, A. R. Rezai (Eds.), Neuromodulation: Comprehensive Textbook of Principles, Technologies, and Therapies (Second Edition), (pp. 513-522). Cambridge: Academic Press.